Conventional care of patients in respiratory distress
most often leads to permanent tracheostomy. Typically,
the following steps are taken in the intensive care unit:
- Oxygen administrated arbitrarily in concentrations
that maintain SaO2 well above 95%.
- Frequent airway suctioning via the tube.
- Supplemental oxygen increased when desaturations
occur.
- Ventilator weaning attempted at the expense of hypercapnia.
- Extubation not attempted unless the patient appears
to be ventilator weaned.
- Extubation to CPAP or low span bi-level positive
airway pressure and continued oxygen therapy.
- Deep airway suctioning by catheterizing the upper
airway along with postural drainage and chest physical
therapy.
- With increasing CO2 retention or hypoxia supplemental
oxygen is increased and ultimately the patient is
reintubated.
- Following re-intubation tracheostomy is thought
to be the only long-term option...or following successful
extubation bronchodilators and ongoing routine chest
physical therapy are used.
- Eventually discharged home with a tracheostomy,
often following a rehabilitation stay for family training.
We have found the following protocol to be quite successful
in preventing tracheostomy and maintaining noninvasive
ventilation:
- Oxygen administration limited only to approach 95%
SaO2.
- mechanical insufflation-exsufflation used via the
tube at 25 to 40 cm H2O to -25 to -40 cm H2O pressures
up to every 10 minutes as needed to reverse oxyhemoglobin
desaturations due to airway mucus accumulation and
when there is ascultatory evidence of secretion accumulation.
Abdominal thrusts are applied during exsufflation.
Tube and upper airway are suctioned following use
of expiratory aids as needed.
- Expiratory aids used when desaturations occur.
- Ventilator weaning attempted without permitting
hypercapnia.
- Extubation attempted whether or not the patient
is ventilator weaned when meeting the following: A.
afebrile B. no supplemental oxygen requirement to
maintain SaO2 >94% C. chest radiograph abnormalities
cleared or clearing D. any respiratory depressants
discontinued E. airway suctioning required less than
1-2x/eight hours F. coryza diminished sufficiently
so that suctioning of the nasal orifices is required
less than once every 6 hours (important to facilitate
use of nasal prongs/mask for post-extubation nasal
ventilation)
- Extubation to continuous nasal ventilation and no
supplemental oxygen.
- Oximetry feedback used to guide the use of expiratory
aids, postural drainage, and chest physical therapy
to reverse any desaturations due to airway mucus accumulation.
- With CO2 retention or ventilator synchronization
difficulties nasal interface leaks were eliminated,
pressure support and ventilator rate increased or
the patient switched from BiPAP-STtm to using a volume
cycled ventilator. Persistent oxyhemoglobin desaturation
despite eucapnia and aggressive use of expiratory
aids indicated impending respiratory distress and
need to re-intubate.
- Following re-intubation the protocol was used for
a second trial of extubation to nasal ventilation...or
following successful extubation bronchodilators and
chest physical therapy were discontinued and the patient
weaned to nocturnal nasal ventilation.
- Discharge home after the SaO2 remained within normal
limits for 2 days and when assisted coughing was needed
less than 4 times per day.
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