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Endarterectomy vs. Stenting
in Treatment of Carotid Artery Stenosis.
The University Hospital Stroke Center is a principal investigational
site for a nationwide, multicenter study comparing outcomes
achieved through stent-assisted angioplasty with outcomes
achieved through endarterectomy. The Carotid Revascularization
Endarterectomy versus Stenting Trial (CREST) is looking
at the use of these procedures in treating carotid artery
stenosis to prevent recurrent strokes in patients who
have had a transient ischemic attack (TIA) or mild ischemic
stroke. Warfarin
vs. Aspirin in Reduced Cardiac Ejection Fraction (WARCEF)
Trial. The University Hospital Stroke
Center is a principal investigational site for a nationwide,
multicenter study sponsored by the National Institute
of Neurological Disorders and Stroke comparing two drugs
commonly used in stroke prevention. The study will determine
which of two commonly used treatments for ischemic stroke
patients — Warfarin, an anticoagulant, or aspirin,
a drug that affects platelet function — is better
for preventing death and stroke in patients with poor
heart function (i.e., patients who have heart failure
or a reduced pumping action of the heart muscle).
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