Neurofibromatosis
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What’s true for football players is true for NF2 patients and their medical team: The best defense is a good, strong offense. For people with NF2, that includes at a minimum, an annual physical exam and a yearly neurological evaluation. Also once a year, they should have an auditory screening, including a test called brainstem auditory-evoked response, even before hearing loss symptoms develop. Auditory tests can detect abnormalities before a problem is visible on an MRI. NF2 patients should also see an ophthalmologist once a year for a thorough evaluation.

Once NF2 tumors develop and become or have the potential to become problematic, the most common treatment is surgery. Some of these tumors are located within a complex part of the anatomy known as the skull base, which is where the undersurface of the brain rests. Removing these tumors as completely and safely as possible often requires the expertise of specialists from several medical disciplines, from neurosurgery to otolarnyngology (ears, noses, and throat) to ophthalmology. University Hospital is supported by an experienced, multidisciplinary skull-base team to address these difficult tumors.

With acoustic neuromas, stereotactic radiosurgery, in which radiation is precisely delivered to the tumor, may be an option. In either case, the earlier the tumors are detected, the greater the chance that they can be removed safely and with the best outcome for the patient.

While the tumors associated with NF2 are benign, it’s their location—on or near the brain, the spinal cord, or the nerves, that makes them surgically challenging. A neurosurgeon may conclude that removing a tumor poses more risks to the patient than benefits. For some tumors, radiation and/or chemotherapy may be recommended.

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