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Hyperthermic Intraperitoneal Cemoperfusion, or HIPEC, is a promising approach to the treatment of advanced abdominal and gynecological cancers. A warmed chemotherapy bath is applied directly to the open abdomen following cytoreductive surgery. HIPEC can be either curative or palliative, depending on the type of tumor and how much of the tumor can be removed surgically. In cases where the tumor is completely removed, HIPEC can also be used as adjuvant therapy to try to keep the tumor from recurring.